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KMID : 1103720100620010023
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Journal of the Korean Society of Radiology
2010 Volume.62 No. 1 p.23 ~ p.28
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The Efficacy of Iopamidol (Pamiray 370® ) in Aortic and Extremity CT Angiography
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Lee Yoo-Jin
Lee Jong-Min
Lee Hee-Jung
Park Ji-Won
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Abstract
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Purpose: To evaluate the clinical safety and radiological feasibility of a domestic iopamidol-based contrast media (Pamiray®370) during an aortic and extremity CT angiography.
Materials and Methods: Between August and December of 2008, 100 patients (M:F=51:49; mean age, 59 years) underwent an aortic and extremity CT angiography using Pamiray®370 based with informed consent. All changes in vital signs, clinical symptoms, and adverse reactions to the contrast media were monitored. Two radiologists assessed the image quality of the CT angiography. A statistical comparison was conducted using an independent t-test and a Mann-Whitney test based on the 100-patient group studied using Optiray®350.
Results: The contrast enhancement of the descending aorta in the arterial phase showed a statistically greater efficacy (p<0.001) of Pamiray®370 compared to Optiray®350, which was the routine contrast media for CT angiography for our institute. Adverse reaction signs were evident in 3%(3/100) of the subjects. All of them showed mild and transient reactions such as vomiting (n=2) and coughing (n=1), with no medical treatment required. Contrast media related symptoms including dizziness (n=7), nausea (n=3), headaches (n=2), and injection site pain (n=1), were noted in 12%(12/100).
Conclusion: The clinical efficacy of Pamiray®370 was acceptable for the aortic and extremity CT angiography, in terms of clinical safety, tolerance, and image quality.
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KEYWORD
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Contrast media, Iopamidol, Tomography, X-Ray Computed
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